The Code of Federal Regulations (CFR) annual edition is the codification of the general and permanent rules published in the Federal Register by the departments and agencies of the Federal Government. It is divided into 50 titles that represent broad areas subject to Federal regulation. The 50 subject matter titles contain one or more individual volumes, which are updated once each calendar year, on a staggered basis.
Each title is divided into chapters, which usually bear the name of the issuing agency. Each chapter is further subdivided into parts that cover specific regulatory areas. Large parts may be subdivided into subparts. All parts are organized in sections, and most citations to the CFR refer to material at the section level.
Summary from US Government Printing Office
The Federal Register (FR) is a daily publication which contains proposed agency rules and federal agency regulations, as well as Executive Orders and Presidential Proclamations. The FR contains final rules and regulations, organized under the title of the issuing agency (and subagency, if applicable), the CFR Title and parts affected, and a brief description of the specific subject of the document. As required by the federal notice-and-comment process, the FR also houses notices to the public of proposes issuance of rules and regulations. "The purpose of these notices is to give interested parties notice and an opportunity to participate in the rule making process." (Summary from U.S. Gov't Printing Office).
While the CFR is updated on an annual basis, the FR is published daily. This distinction positions the FR as the most up-to-date rules, regulations, and actions taken by agencies to affect such rules or regulations. As a result, the FR can be used to "update" rules and regulations cited in the CFR.
Source: http://www.uspto.gov/main/glossary/lawsandrules.htm
Each volume of the CFR is labeled with the title contained in that volume. Citations to the CFR typically follow a “[title] CFR [section]” format, so finding a regulation by CFR citation is simple. To find relevant regulations without a citation, see the following list of titles:
Title 1: General Provisions
Title 2: Grants and Agreements
Title 3: The President
Title 4: Accounts
Title 5: Administrative Personnel
Title 6: Domestic Security (Cover Only)
Title 7: Agriculture
Title 8: Aliens and Nationality
Title 9: Animals and Animal Products
Title 10: Energy
Title 11: Federal Elections
Title 12: Banks and Banking
Title 13: Business Credit and Assistance
Title 14: Aeronautics and Space
Title 15: Commerce and Foreign Trade
Title 16: Commercial Practices
Title 17: Commodity and Securities Exchanges
Title 18: Conservation of Power and Water Resources
Title 19: Customs Duties
Title 20: Employees' Benefits
Title 21: Food and Drugs
Title 22: Foreign Relations
Title 23: Highways
Title 24: Housing and Urban Development
Title 25: Indians
Each volume of the CFR is labeled with the title contained in that volume. Citations to the CFR typically follow a “[title] CFR [section]” format, so finding a regulation by CFR citation is simple. To find relevant regulations without a citation, see the following list of titles:
Title 26: Internal Revenue
Title 27: Alcohol, Tobacco and Firearms
Title 28: Judicial Administration
Title 29: Labor
Title 30: Mineral Resources
Title 31: Money and Finance: Treasury
Title 32: National Defense
Title 33: Navigation and Navigable Waters
Title 34: Education
Title 35: No Longer in Use (formerly Panama Canal)
Title 36: Parks, Forests, and Public Property
Title 37: Patents, Trademarks, and Copyrights
Title 38: Pensions, Bonuses, and Veterans' Relief
Title 39: Postal Service
Title 40: Protection of Environment
Title 41: Public Contracts and Property Management
Title 42: Public Health
Title 43: Public Lands: Interior
Title 44: Emergency Management and Assistance
Title 45: Public Welfare
Title 46: Shipping
Title 47: Telecommunication
Title 48: Federal Acquisition Regulations System
Title 49: Transportation
Title 50: Wildlife and Fisheries